Abstract
WHILE many transplanted animal tumours may be cured if treated with chemotherapeutic agents the day after implantation, there are few reports of the regular cure of such tumours if treatment is delayed until the tumours are advanced and large (that is, more than 20 per cent of the body-weight). This communication reports the regular cure of large, well-established mouse plasma cell tumours (ADJ–PG5) (ref. 1) up to 21 days old and 5 g in weight with a single intraperitoneal dose of N, N-di-2-chloroethyl aniline (aniline mustard, CB 1074) (I).
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WHISSON, M., CONNORS, T. Drug-induced Regression of Large Plasma Cell Tumours. Nature 205, 406 (1965). https://doi.org/10.1038/205406a0
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DOI: https://doi.org/10.1038/205406a0
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