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Bronchoconstrictor Action of Bradykinin, Kallidin and Eledoisin

Nature volume 205, pages 403–404 (1965)Cite this article

Abstract

THE interesting observation of Gjuriš and Westermann that bradykinin differs from 5-hydroxytryptamine in its action on the tracheobronchial muscle of the guinea-pig accords with previous findings. For example, Jänkälä and Virtama1 concluded from radiography that 5-hydroxytryptamine “causes vigorous constriction of all the constrictable bronchial tree of the guinea-pig”, whereas “bradykinin apparently only affects the respiratory bronchioles”. I am glad that Gjuriš and Westermann support the suggestion we made some tune ago2, that bradykinin may also affect the smooth muscles of the pleural surface of the lung.

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References

  1. Jänkälä, E. O., and Virtama, P., Ann. Med. exp. Fenn., 41, 436 (1963).

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Authors and Affiliations

  1. Department of Pharmacological Research, Parke, Davis and Co., Hounslow, Middlesex

    H. O. J. COLLIER

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  1. H. O. J. COLLIER
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COLLIER, H. Bronchoconstrictor Action of Bradykinin, Kallidin and Eledoisin. Nature 205, 403–404 (1965). https://doi.org/10.1038/205403a0

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