Abstract
THE pathogenicity, in the classic sense, of bacterial L-phase cells has yet to be conclusively demonstrated. The association of the L-phase of certain bacteria with diverse clinical states has been noted in the past, and this association is being reported more frequently as knowledge and interest in these forms have increased1–9. Such reported investigations lead to the assumption that host resistance mechanisms tend to create the L-phase of a bacterium. Experiments designed to determine the possible pathogenicity of the bacterial L-phase have usually ignored the host. It is not unreasonable to assume that the L-phase is the bacterial form most readily handled by normal host resistance mechanisms.
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GODZESKI, C., BRIER, G., GRIFFITH, R. et al. Association of Bacterial L-Phase Organisms in Chronic Infections. Nature 205, 1340 (1965). https://doi.org/10.1038/2051340a0
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DOI: https://doi.org/10.1038/2051340a0
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