Abstract
Friedhoff and Van Winkle1,2 have reported the presence of 3,4-dimethoxyphenylethylamine in the urine of 15 of 19 schizophrenic patients, while they could not find this amine in the urine of 14 normal subjects. More recently these authors3 have reported the urinary excretion of radioactive 3,4-dimethoxyphenylethylamine and 3,4-dimethoxyphenylacetic acid by 5 schizophrenic patients after the intravenous administration of radioactive 3,4-dihydroxyphenylethylamine (dopamine). Takesada et al.4, using a different technique for the recovery of amines from urine, found 3,4-dimethoxyphenylethylamine in the urines of 70 of 78 schizophrenic patients, but detected it also in the urines of 21 of 46 normal subjects.
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References
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PERRY, T., HANSEN, S. & MACINTYRE, L. Failure to detect 3,4-Dimethoxyphenylethylamine in the Urine of Schizophrenics. Nature 202, 519–520 (1964). https://doi.org/10.1038/202519a0
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DOI: https://doi.org/10.1038/202519a0
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