Abstract
IN comparative experiments in mice with ovarian grafts into the spleen, or into the kidney and liver, it has been shown that the tumours originating in the latter are microtumours as compared to the macrotumours in the spleen. The difference is not due to influences from the site itself: when grafting one ovary into the spleen and the other into the kidney (or liver) of the same animal (‘combined’ grafts) in both the intrasplenic and intrarenal (or intrahepatic) grafts no more than microtumours appear1,2 (Fig. 1).
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lipschutz, A., Proc. Fifth Panamer. Congr. Endocrinol., 205 (1963); Acta Union Intern. Cancer (in the press).
Lipschutz, A., and Cerisola, H., Nature, 193, 145 (1962).
Biskind, M. S., and Biskind, G. R., Proc. Soc. Exp. Biol. Med., 55, 176 (1944). Biskind, G. R., et al., Cancer Res., 10, 309 (1950); 13, 216 (1953).
Kullander, S., Acta Endocrinol., Supp., 22, (1954); 27 (1956).
Fels, E., and Foglia, V., Acta Endocrinol., 34, 1 (1960); III Weltkongress Gynaecol. and Geburtsh., No. 213 (1961).
Ely, Ch. E., Cancer Res., 19, 37 (1959).
Lipschutz, A., Mardones, E., Bruzzone, S., and Iglesias, R., Acta Union Internat. Cancer, 16, 203 (1960).
Howell, J. S., Marchant, J., and Orr, J. W., Brit. J. Cancer, 8, 635 (1954).
Marchant, J., Acta Union Internat. Cancer, 15, 196 (1959); Brit. J. Cancer, 14, 514, 519 (1960); Morphol. Precurs. Cancer, edit. by Severi, L., 709 (Perugia, 1962).
Mandl, A. M., and Zuckerman, S., J. Endocrinol., 13, 243, 262 (1956).
Ely, Ch. E., Proc. Soc. Exp. Biol. Med., 105, 111 (1960); Cancer Res., 20, 1625 (1960).
Furth, J., et al., Amer. J. Cancer, 28, 66 (1936); Cancer Res., 7, 241, 246 (1947); 17, 454 (1957).
Lipschutz, A., Acta Union Internat. Cancer, 16, 149 (1960).
Gardner, W. U., Proc. Amer. Assoc. Cancer Res., 2, 300 (1958); J. Nat. Cancer Inst., 26, 829 (1961).
Lipschutz, A., and Panasevich, V. I. (in preparation).
Lipschutz, A., Voss, H. E., et al., C.R. Soc. Biol., Paris, 90, 1139, 1332 (1923); 91, 865 (1924); 92, 1176, 1178, 1179 (1925); Pflüger's Arch., 211, 266, 279, 305, 745 (1926).
Takewaki, K., J. Fac. Sci. Univ. Tokyo, 4, 155 (1933); Proc. Japan Acad., 25, 50 (1950); Annot. Zool. Japon., 31, 34 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LIPSCHUTZ, A., PANASEVICH, V. & ALVAREZ, A. New Experimental Evidence of Tumorigenic Hormonal Imbalances. Nature 202, 503–504 (1964). https://doi.org/10.1038/202503a0
Issue Date:
DOI: https://doi.org/10.1038/202503a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
