Abstract
Meselson, Stahl and Vinograd1 first described the equilibrium density gradient technique for the examination of DNA in the analytical ultracentrifuge, and the technique has since been used to investigate a number of macromolecules2. In the past, density gradient investigations of lipoproteins have been limited to the preparative ultracentrifuge. This communication reports the banding of human plasma lipoproteins in sucrose–sodium bromide density gradients at equilibrium in the analytical ultracentrifuge.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Meselson, M., Stahl, F. W., and Vinograd, J., Proc. U.S. Nat. Acad. Sci., 43, 581 (1957).
Vinograd, J., and Hearst, J. E., Fortsch. Chem. organ. Naturstoffe, 20, 372 (1962).
DeLalla, O. F., and Gofman, J. W., in Methods of Biochemical Analysis, edit. by Glick, D., 1, 459 (Interscience Pub., Inc., New York, 1954).
Briner, W. W., Riddle, J. W., and Cornwell, D. G., Proc. Soc. Exp. Biol. and Med., 101, 784 (1959).
Ifft, J. B., Voet, D. H., and Vinograd, J., J. Phys. Chem., 65, 1138 (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ADAMS, G., SCHUMAKER, V. Analytical Equilibrium Density Gradient Ultracentrifugation of Human Plasma Lipoproteins. Nature 202, 490–491 (1964). https://doi.org/10.1038/202490a0
Issue Date:
DOI: https://doi.org/10.1038/202490a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
