Abstract
ANTIGEN–ANTIBODY complexes can dissociate under suitable conditions (increased ionic strength, extreme pH values), which indicates that the reaction depends on the medium and is reversible. It can, therefore, be assumed that the reaction between antigen and antibody is not a genuine chemical reaction. Disregarding the specificity of the combination of antigen with antibody, the similarity between it and the formation of complexes by adsorption is very great.
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WEINBACH, R. Mechanism of Antigen–Anti body Reactions. Nature 202, 409–410 (1964). https://doi.org/10.1038/202409a0
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DOI: https://doi.org/10.1038/202409a0
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