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Carcinogen-induced Melanotic Tumours of the Tylotrich (Hair) Follicle

Abstract

IN skin of the Syrian golden hamster, clusters of pigmented dendritic cells are found occasionally around certain hair follicles1. These areas of pigment are visible to the eye as small black spots. Ghadially and Barker1 consider these clusters of pigmented cells to be normal, not nevi, and their studies of skin treated repeatedly with 9,10-dimethyl-1,2-benzanthracene (DMBA) indicate that melanotic tumours arise at these particular sites.

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References

  1. Ghadially, F. N., and Barker, J. F., J. Path. Bact., 79, 263 (1960).

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  2. Straile, W. E., Amer. J. Anat., 106, 133 (1960).

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STRAILE, W. Carcinogen-induced Melanotic Tumours of the Tylotrich (Hair) Follicle. Nature 202, 403–404 (1964). https://doi.org/10.1038/202403a0

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