Abstract
TETRACYCLIN has been shown to be incorporated into different tissues undergoing necrobiotic changes, and the presence of the drug can be detected by its fluorescence properties. Consequently, tetracyclin fluorescence has been seen in neoplastic tissues1, in gastric and cutaneous ulcers2,3, and in bacterial foci4. Our recent investigations on viral infection in organ rudiments in vitro seemed to offer a good possibility for following tetracyclin incorporation into viral lesions.
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References
Vassar, P. S., Saunders, A. M., and Culling, C. F. A., Amer. Med. Assoc. Arch. Pathol., 69, 613 (1960).
Häkkinen, I., and Hartiala, K., Ann. Med. Exp. Fenn., 37, 115 (1959).
Mustakallio, K. K., The Lancet, 721 (1962).
Málek, P., Kolc, J., and Žak, F., Antimicrobial Agents Annual, 1960, 206 (Plenum Press, New York, 1961).
Saxén, L., Vainio, T., and Toivonen, S., J. Nat. Cancer Inst., 29, 597 (1962).
Vainio, T., Saxén, L., and Toivonen, S., Virology, 20, 380 (1963).
Vainio, T., Saxén, L., Toivonen, S., J. Nat. Cancer Inst., 31, 1533 (1963).
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SAXÉN, L., VAINIO, T. Tetracyclin Fluorescence as a Marker for Detection of Viral Lesions in vitro. Nature 201, 936–937 (1964). https://doi.org/10.1038/201936b0
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DOI: https://doi.org/10.1038/201936b0
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