Abstract
STACEY et al.1,2 reported that the glucosaminidie linkages in several glucosaminides, chitosan and ψ-heparin (N-desulphated heparin), were cleaved deaminatively to produce 2,5-anhydromannose as the main product with nitrous acid. Later, similar observations were reported by Matsushima and Fujii3 on the deamination of the hydrazinolysed product of chondroitin sulphate. On the other hand, Yosizawa and Sato4,5 presented quantitative data as to the formation of 2,5-anhydrohexoses from N-deacetylated hexosamines in the partially N-deacetylated mucopolysaccharides by the direct deamination with nitrous acid.
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YOSIZAWA, Z. Deamination of the Partially N-Deacetylated Mucopolysaccharides. Nature 201, 926–927 (1964). https://doi.org/10.1038/201926b0
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DOI: https://doi.org/10.1038/201926b0
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