Abstract
PRIMYCIN, which has strong antituberculotic characteristics, belongs to the group of Sakaguchi-positive antibiotics. With regard to its infra-red spectrum1, which resembles that of streptomycin, its closer identification appeared to be reasonable. Absorption maxima of the ultra-violet spectra of primycin and of simple aliphatic guanidines2, characteristic of the azomethin (= C = N—H) bond, were detected in the 205–220 mµ wave-length region. So the ultra-violet spectra of guanidino antibiotics were investigated.
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References
Szilágyi, I., Vályi-Nagy, T., Szabó, I., and Keresztes, T., Nature, 193, 234 (1962); Mikrochim. Acta, 4, 671 (1962).
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Dosskochilova, D., and Vondrachek, M., Antibiotiky, 7, 649 (1961).
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SZILÁGYI, I., VÁLYI-NAGY, T., SZABÓ, I. et al. Identification of Primycin and Other Guanidino Antibiotics. Nature 201, 81–82 (1964). https://doi.org/10.1038/201081a0
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DOI: https://doi.org/10.1038/201081a0
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