Abstract
IN publications describing a series of experiments a group of Dutch investigators1 recently gave quantitative results on the radioprotective power of different chemical agents at the cellular level in an in vitro system. Assayed by the degree to which radiation damage, as measured by the loss of reproductive integrity of human kidney cells, was prevented, it was shown that the protective activity of cysteamine depends on the concentration of the compound used for treatment.
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References
Vergroesen, A. J., Vos, O., and Budke, L., Nature, 194, 100 (1962) Vos, O., Budke, L., and Vergroesen, A. J., Intern. J. Rad. Biol., 5, 543 (1962). Vergroesen, A. J., Budke, L., and Vos, O., Intern. J. Rad. Biol., 6, 117 (1963).
Révész, L., and Norman, U., J. Nat. Cancer Inst., 25, 1041 (1960). Révész, L., Glas, U., and Hilding, G., Nature, 198, 260 (1963).
Révész, L., Bergstrand, H., and Modig, H., Nature, 198, 1275 (1963).
Ellman, G. L., Arch. Biochem. Biophys., 82, 70 (1959).
Schrek, R., Amer. J. Cancer, 28, 389 (1936).
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RÉVÉSZ, L., BERGSTRAND, H. Radiation Protection by Cysteamine and Cellular Sulphydryl Levels. Nature 200, 594–595 (1963). https://doi.org/10.1038/200594a0
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DOI: https://doi.org/10.1038/200594a0
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