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Re-utilization of Deoxyribonucleic Acid from Cells other than Leucocytes

Abstract

In vivo re-utilization of DNA by mammalian cells to an extent demonstrable with autoradiography was shown by Fichtelius and Diderholm1, and has since been reported from several laboratories. Leucocytes, especially lymphocytes, have been assumed to be the DNA-vectors responsible for this re-utilization2–4. It has, however, been demonstrated that DNA from sarcoma cells can also be re-utilized in vivo4. The work reported here shows that DNA from transplanted tissue of different kinds can be re-utilized in the formation of other cells.

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References

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FICHTELIUS, K., GROTH, O. Re-utilization of Deoxyribonucleic Acid from Cells other than Leucocytes. Nature 200, 587–588 (1963). https://doi.org/10.1038/200587a0

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