Abstract
CYSTEINE sulphinic acid (CSA) is an intermediary product in the conversion of cysteine to taurine in the rat1. Cysteic acid (CA) has also been shown to be a precursor of taurine in the rat2. CSA and, to a lesser extent, CA increase the production of carbon dioxide by liver and brain tissue from some mammalian species (the rat3, the rabbit4, and the dog5), although not from others (the horse5 and the cat6). These findings indicate that the formation of taurine in some mammalian species may proceed along the pathways shown in Fig. 1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Chapeville, F., and Fromageot, P., Biochem. Biophys. Acta, 17, 275 (1955).
Awapara, J., and Wingo, W. J., J. Biol. Chem., 203, 189 (1953).
Bergeret, B., Chatagner, F., and Fromageot, C., Biochem. Biophys. Acta, 17, 128 (1955).
Bergeret, B., Chatagner, F., and Fromageot, C., Biochem. Biophys. Acta, 22, 329 (1956).
Sörbo, B., and Heyman, T., Biochem. Biophys. Acta, 23, 624 (1957).
Hope, D. B., Biochem. J., 59, 497 (1955).
Davison, A. N., Biochem. Biophys. Acta, 19, 66 (1956).
Lavine, T. F., J. Biol. Chem., 113, 583 (1936).
Friedmann, E., Beitr. Chem. Physiool. Path., 2, 433 (1902).
Müller, P. B., and Langemann, H., J. Neurochem., 9, 399 (1962).
Smith, jun., L. H., Sullivan, M., and Huguley, jun., C. M., J. Clin. Invest., 40, 656 (1961).
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).
Huynh Vinh An, and Fromageot, P., Bull. Soc. Chim. Biol., 42, 221 (1960).
Ekdahl, P.-H., and Stenram, U., Acta Chir. Scand., 115, 189 (1958).
Patrick, A. D., Biochem. J., 83, 248 (1962).
Sjövall, J., Clin. Chim. Acta, 5, 33 (1960).
Sjövall, J., Proc. Soc. Exp. Biol. and Med., 100, 676 (1959).
Eldjarn, L., Scand. J. Clin. Lab. Invest., 6, Supp. 13 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
JACOBSEN, J., SMITH, L. Comparison of Decarboxylation of Cysteine Sulphinic Acid-1-14C and Cysteic Acid-1-14C by Human, Dog, and Rat Liver and Brain. Nature 200, 575–577 (1963). https://doi.org/10.1038/200575b0
Issue Date:
DOI: https://doi.org/10.1038/200575b0
This article is cited by
-
Impaired bile acid metabolism with defectives of mitochondrial-tRNA taurine modification and bile acid taurine conjugation in the taurine depleted cats
Scientific Reports (2020)
-
Taurine homeostasis requires de novo synthesis via cysteine sulfinic acid decarboxylase during zebrafish early embryogenesis
Amino Acids (2013)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
