Induction of Fibrosarcoma in the Primate Tamarinds nigricollis

Abstract

ATTEMPTS to induce malignant neoplasms in monkeys have not met with the success that has been achieved in other species. The rarity of spontaneous neoplasms in monkeys suggests that these animals are more resistant to the development of malignant disease than man and other species. There have been no specific references, however, to the use of the South American marmoset, Tamarinus nigricollis, in the experimental induction of neoplasms. A recent review by Kent¹ indicates that attempts at the production of malignant disease by the application of polycyclic hydrocarbons in monkeys have failed.