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Formation and Structure of the Collagen Fibril

Nature volume 198, pages 798–799 (1963)Cite this article

Abstract

IT seems to be generally assumed that collagen fibrils are solid structures, formed by the aggregation of large numbers of long, extremely thin, particles of tropocollagen1. However, during an investigation into collagen formation in the avascular granulomas produced on the surface of peritoneal implants of egg-white and agar2, the collagen fibrils appeared to develop as tubular structures.

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References

  1. Gross, J., Highberger, J. H., and Schmitt, F. O., Proc. U.S. Nat. Acad. Sci., 40, 679 (1954).

    Article  ADS  CAS  Google Scholar 

  2. Curran, R. C., and Ager, J. A. M., Nature, 193, 494 (1962).

    Article  ADS  CAS  Google Scholar 

  3. Karnovsky, M. J., J. Biophys. and Biochem. Cytol., 11, 729 (1961).

    Article  CAS  Google Scholar 

  4. Meyer, K., Physiol. Rev., 27, 335 (1947).

    Article  CAS  Google Scholar 

  5. Rigby, B. J., Hirai, N., Spikes, J. D., and Eyring, H., J. Gen. Physiol., 43, 265 (1959).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, St. Thomas's Hospital Medical School, London, S.E.1

    R. C. CURRAN & A. E. CLARK

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  1. R. C. CURRAN
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  2. A. E. CLARK
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CURRAN, R., CLARK, A. Formation and Structure of the Collagen Fibril. Nature 198, 798–799 (1963). https://doi.org/10.1038/198798a0

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