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Salivary Excretion and Inactivation of Some Penicillins

Abstract

SINCE no data seem to be available in the literature concerning salivary excretion of the new semi-synthetic penicillins, salivary concentrations were ascertained after intramuscular administration of procain-penicillin, methoxyphenyl-penicillin, and æthoxyphenyl-penicillin (15,000 U/kg). For comparison G-penicillin potassium was administered in an equal dosage intravenously, intramuscularly and per os, dibenzylæthylendiamindi (DBED)-penicillin per os and in a ten-fold dosage dimethoxyphenyl-penicillin intramuscularly.

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ADLER-HRADECKY, C., KELENTEY, B. Salivary Excretion and Inactivation of Some Penicillins. Nature 198, 792–793 (1963). https://doi.org/10.1038/198792b0

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