Abstract
HOKIN and HOKIN1 have shown that acetylcholine stimulates the uptake of phosphorus-32 into the phosphatidic acid of guinea pig brain microsomes when they are incubated with a system which generates adenosine-triphosphate-32 (AT 32P). This has been used as evidence for the role of phosphatidic acid in active transport across membranes, and later work2 has shown that the process is influenced by the fatty acids present. We considered that it would be of interest to extend these experiments to rats deficient in essential fatty acids3.
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References
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DE PURY, G., COLLINS, F. Uptake of Phosphorus-32 by Brain Microsomal Phosphatidic Acid in Rats Deficient in Essential Fatty Acids. Nature 198, 788–789 (1963). https://doi.org/10.1038/198788a0
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DOI: https://doi.org/10.1038/198788a0
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