Abstract
IN a stimulating article in Nature Pullman and Pullman1 direct attention to the fact that many essential biomolecules contain resonance systems with delocalized π-electrons. The authors are right in stressing their importance for the function of these molecules in life processes; but the authors' claim that this is “one essential, although apparently hitherto unnoticed aspect of biochemistry” cannot be accepted. I am convinced that many biochemists are already quite familiar with it.
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References
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LEMBERG, R. Electronic Delocalization and Biochemical Evolution. Nature 198, 1224–1225 (1963). https://doi.org/10.1038/1981224b0
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DOI: https://doi.org/10.1038/1981224b0
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