Abstract
USING a new technique, Boyden1 has shown that rabbit serum after incubation in vitro with an antigen-antibody precipitate becomes strongly chemotactic to rabbit granulocytes. Prior heating of the serum to 56° for 30 min was found to prevent activation of the chemotactic principle which, once formed, was relatively heat-stable.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Boyden, S., J. Exp. Med., 115, 453 (1962).
Hurley, J. V., and Spector, W. G., J. Path. Bact., 82, 403 (1961).
Hurley, J. V., and Spector, W. G., J. Path. Bact., 82, 421 (1961).
Harris, H., J. Path. Bact., 66, 135 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HURLEY, J. Incubation of Serum with Tissue Extracts as a Cause of Chemotaxis of Granulocytes. Nature 198, 1212–1213 (1963). https://doi.org/10.1038/1981212a0
Issue Date:
DOI: https://doi.org/10.1038/1981212a0
This article is cited by
-
Mechanism of the phlogogenic activity of leukocytes
Bulletin of Experimental Biology and Medicine (1969)
-
Leukoegresin: a Factor from Rabbit Skin associated with Leucocytic Emigration in the Arthus Reaction
Nature (1968)
-
Autoimmunity and Inflammation
Nature (1964)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.