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Properties of Phage-neutralizing Antibodies produced by New-born Rabbits

Abstract

THE new-born rabbit is known to show an immunological reactivity which differs in several respects from that of the mature animal. We have found that rabbits injected at birth with coliphage T2 show, after a short delay, phage-neutralizing activity in their sera which appears to be antibody. These antibodies, however, differ in several aspects from the phage-neutralizing antibodies produced by adult animals immunized with the same bacteriophage.

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References

  1. Adams, M. H., in, Bacteriophages (New York, Interscience Publishers, 1959).

    Google Scholar 

  2. Barlow, J. L., VanVunakis, H., and Levine, L., J. Immunol., 80, 349 (1958).

    CAS  PubMed  Google Scholar 

  3. Pillemer, L., Blum, L., Lepow, I. H., Ross, O. A., Todd, E. W., and Wardlaw, A. C., Science, 120, 279 (1954).

    Article  ADS  CAS  Google Scholar 

  4. Nelson, R. A., J. Exp. Med., 108, 515 (1958).

    Article  CAS  Google Scholar 

  5. Cowan, K. M., J. Immunol., 88, 476 (1962).

    CAS  PubMed  Google Scholar 

  6. Stelos, P., J. Infect. Dis., 102, 103 (1958).

    Article  CAS  Google Scholar 

  7. Bauer, D. C., and Stawitsky, A. B., Proc. U.S. Nat. Acad. Sci., 47, 1667 (1961).

    Article  ADS  CAS  Google Scholar 

  8. Mathies, M., and Stawitsky, A. B., Fed. Proc., 21 (2), 26 (1962).

    Google Scholar 

  9. Harris, J. E., Siminovitch, L., McCulloch, E. C., and Cinader, B., Fed. Proc., 21 (2), 17 (1962).

    Google Scholar 

  10. Svehag, S. E., and Mandel, B., Fed. Proc., 21 (2), 29 (1962).

    Google Scholar 

  11. Uhr, J. W., Finkelstein, M. S., and Baumann, J. B., J. Exp. Med., 115, 655 (1962).

    Article  CAS  Google Scholar 

  12. Kalmutz, S. E., Nature, 193, 851 (1962).

    Article  ADS  CAS  Google Scholar 

  13. Bellenti, J. A., Eitzman, D. V., and Smith, R. T., Fed. Proc., 21 (2), 30 (1962).

    Google Scholar 

  14. Pernis, B., and Thorbecke, G. J. (in preparation).

Download references

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PERNIS, B., GHEZZI, I. & TURRI, M. Properties of Phage-neutralizing Antibodies produced by New-born Rabbits. Nature 197, 807–808 (1963). https://doi.org/10.1038/197807a0

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