Abstract
IN a previous communication1 it was shown that there is a correlation between the ability of an agent to inhibit antibody production and its ability to inhibit tumour growth. Single doses of agent and T.A.B. vaccine were given simultaneously, and sera were titrated 9 days later. Under these conditions 5 of 12 compounds known to be active inhibitors of tumours in man or laboratory animals were also found to depress antibody production to a moderate or a marked extent. Of 12 compounds which were not tumour-inhibitory, none did so, even in lethal doses.
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References
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BERENBAUM, M. A Screen for Agents inhibiting the Immune Response and the Growth of Tumours. Nature 196, 384–385 (1962). https://doi.org/10.1038/196384a0
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DOI: https://doi.org/10.1038/196384a0
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