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Trypsin Inhibitors produced by Clostridium botulinum Cultures

Abstract

TRYPSIN inhibitors have been demonstrated in a large variety of biological material, involving, among others, pancreas, milk, egg-white, blood, placenta, urine, skin, gut parasites, beans, peas, potatoes1 and bacteria2. In this communication the presence of trypsin-inhibiting material in the culture supernatants of Clostridium botulinum, types A, B and E, is reported.

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References

  1. A survey is given in: Kiermeyer, F., and Semper, G., Z. Lebensmittelunters. Forschung, 111, 282 (1960).

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  2. Sandvik, O. (personal communication).

  3. Bonventre, P. F., and Kempe, L. L., J. Bacteriol., 79, 18 (1960).

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  4. Gordon, M., Fiock, M. A., Yarinsky, A., and Duff, J. T., J. Bacteriol., 74, 533 (1957).

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  5. In Northrop, J. H., Kunitz, M., and Herriot, R. M., Crystalline Enzymes, second ed., 310 (1948).

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HÖYEM, T., SKULBERG, A. Trypsin Inhibitors produced by Clostridium botulinum Cultures. Nature 195, 922–923 (1962). https://doi.org/10.1038/195922a0

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