Abstract
IN a previous report1, the finding of serotonin and of amine oxidase activity in the venom of Heloderma horridum was recorded. The purpose of this communication is to present results of studies which demonstrate that tissue homogenates of selected organs from two animals of this species degrade serotonin readily in an in vitro test system. In addition, the findings with respect to efforts to inhibit this activity with various compounds will be noted.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Zarafonetis, C. J. D., and Kalas, J. P., Amer. J. Med. Sci., 240, 764 (1960).
Zarafonetis, C. J. D., and Kalas, J. P., Copeia, No. 3, 240 (1960).
Udenfriend, S., et al., in Methods of Biochemical Analysis, edit. by Glick, D., 6 (Interscience Pub. Inc., New York, 1958).
Davidson, A. N., Physiol. Rev., 38, 729 (1958).
Zarafonetis, C. J. D., and Kalas, J. P. (unpublished results).
Zarafonetis, C. J. D., and Kalas, J. P., Proc. Soc. Exp. Biol. and Med., 105, 560 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ZARAFONETIS, C., KALAS, J. Serotonin Degradation by Homogenates of Tissues from Heloderma horridum, the Mexican Beaded Lizard. Nature 195, 707–708 (1962). https://doi.org/10.1038/195707a0
Issue Date:
DOI: https://doi.org/10.1038/195707a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
