Abstract
PROOF for the separate localization on the human X-chromosome of the protanopia-protanomaly alleles and of the deuteranopia-deuteranomaly alleles requires the demonstration of: (1) non-allelic compound hemizygous males which in conditions of equilibrium should occur once among a thousand men (one in eighty colour-blind men) or of (2) crossover males in families combining both classes of defect.
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KALMUS, H. Distance and Sequence of the Loci for Protan and Deutan Defects and for Glucose-6-Phosphate Dehydrogenase Deficiency. Nature 194, 215 (1962). https://doi.org/10.1038/194215a0
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DOI: https://doi.org/10.1038/194215a0
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