Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Incorporation of Host Nuclear Materials into Transplanted Tumour Cells in Surgical Wounds

Nature volume 194, pages 193–194 (1962)Cite this article

Abstract

AREAS of acute inflammation contain extracellular deoxyribonucleic acid (DNA) derived principally from dead leucocytes1–3. It has been suggested that components of this DNA may be re-utilized by proliferating cells; but direct evidence for this concept has not been reported3,4.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Bunting, H., Yale J. Biol. and Med., 22, 521 (1949).

    Google Scholar 

  2. Sherry, S., Tillett, W. S., and Christensen, L. R., Proc. Soc. Exp. Biol. and Med., 68, 179 (1948).

    Article  CAS  Google Scholar 

  3. Dumont, A. E., Ann. Surg., 150, 799 (1959).

    Article  CAS  Google Scholar 

  4. Fichtelius, K. E., in Biological Activity of the Leucocyte, 31 (Little, Brown and Co., Boston, 1961).

    Google Scholar 

  5. Bull. No. 142 (revised), Tritiated Thymidine (Schwarz Bioresearch, Inc., Orangeburg, New York, 1961).

  6. Rubini, J. R., Cronkite, E., Bond, V. P., and Fliedner, T. M., J. Clin. Invest., 39, 909 (1960).

    Article  CAS  Google Scholar 

  7. Borenfreund, E., and Bendich, A., J. Biophys. and Biochem. Cytol., 9, 81 (1961).

    Article  CAS  Google Scholar 

  8. MacDonald, R. A., Surgery, 46, 376 (1959).

    CAS  PubMed  Google Scholar 

  9. Baserga, R., Kisieleski, W. E., and Halvorsen, K., Cancer Res., 20, 910 (1960).

    CAS  PubMed  Google Scholar 

  10. Tonna, E. A., and Cronkite, E., J. Bone and Joint Surg., 43, 352 (1961).

    Article  Google Scholar 

  11. Dancis, J., and Balis, M. E., J. Biol. Chem., 207, 367 (1954).

    CAS  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. ALLAN E. DUMONT: Senior Research Fellow, U.S. Public Health Service, National Institutes of Health.

Authors and Affiliations

  1. Departments of Surgery, Medicine and Pathology, New York University School of Medicine,

    ALLAN E. DUMONT, JOHN H. AYVAZIAN & ROBERT T. McCLTUKEY

Authors
  1. ALLAN E. DUMONT
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. JOHN H. AYVAZIAN
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. ROBERT T. McCLTUKEY
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

DUMONT, A., AYVAZIAN, J. & McCLTUKEY, R. Incorporation of Host Nuclear Materials into Transplanted Tumour Cells in Surgical Wounds. Nature 194, 193–194 (1962). https://doi.org/10.1038/194193a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/194193a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing