Abstract
WHILE preparing a manuscript on the metabolism of Amphibia to appear in a forthcoming book1, I was struck by an interesting relationship between the occurrence of the ornithine-urea cycle2 in the liver of vertebrates and the deoxyribonucleic acid (DNA) content of their somatic cells.
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References
Brown, jun., G. W., in The Physiology of Amphibia, edit. by Moore, J. A. (Academic Press, New York) (in the press).
Krebs, H. A., and Henseleit, K., Z. physiol. Chem., 210, 33 (1932).
Vendrely, R., in The Nucleic Acids, edit. by Chargaff, E., and Davidson, J. N., 2, 155 (Academic Press, New York, 1955).
Brown, jun., G. W., and Cohen, P. P., Biochem. J., 75, 82 (1960).
Cohen, P. P., and Brown, jun., G. W., in Comparative Biochemistry, edit. by Florkin, M., and Mason, H. S., 2, 161 (Academic Press, New York, 1960).
Mirsky, A. E., and Ris, H., J. Gen. Physiol., 34, 451 (1951).
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BROWN, G. Urea Cycle and Cellular Deoxyribonucleic Acid Content. Nature 194, 1279–1280 (1962). https://doi.org/10.1038/1941279b0
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DOI: https://doi.org/10.1038/1941279b0
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