Abstract
A NEW cyclic process has been developed for isolating a microbial polysaccharide from fermented broth. The usual method has been by addition of a water-miscible solvent in which the polysaccharide is insoluble, for example, methanol or ethanol1,2. Because of the high viscosity of most microbial polymers in water solutions, it is difficult to obtain concentrations greater than 1.5 per cent in the fermented broth; consequently, large amounts of solvent are required to isolate and purify the polysaccharide.
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ALBRECHT, W., ROGOVIN, S. & GRIFFIN, E. Recovery of Microbial Polysaccharide B-1459 with a Quaternary Ammonium Compound. Nature 194, 1279 (1962). https://doi.org/10.1038/1941279a0
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DOI: https://doi.org/10.1038/1941279a0
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