Abstract
THE modes of regeneration of large bodies formed by the action of penicillin are well known to-day. This is not so, however, for spheroplasts produced by lysozyme. The possibility of their reversion to the bacillary form is quoted by Zinder and Arndt1, although it is denied by others2. So far as we know, no morphological study of this reversion has yet been published. If lysozyme and penicillin act on the same layer of the cell wall3, the corresponding forms might be expected to behave in the same way during the regeneration process.
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References
Zinder, N. D., and Arndt, W. F., Proc. U.S. Nat. Acad. Sci., 42, 586 (1956).
Fraser, D., quoted by McQuillen, “Bacterial Protoplasts” in The Bacteria, 1 (Academic Press, Inc., New York and London, 1960).
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Nermut, M. V., Folia Biol. (Praha), 3, 149 (1957).
Nermut, M. V., L-Cycle of Bacteria, its Biological and Medical Significance (SZdN, Praha, 1960) (in Czech with English summary).
Pitzurra, M., and Szybalski, W., J. Bact., 77, 614 (1959).
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NERMUT, M., SVOBODA, A. Reversion of Spheroplasts produced by Lysozyme into Rods in Proteus vulgaris. Nature 193, 396–397 (1962). https://doi.org/10.1038/193396b0
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DOI: https://doi.org/10.1038/193396b0
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