Abstract
JACOBSON et al.1 have reported that the hyperplastic erythroid tissue of anæmic rabbits was more resistant to the effects of ionizing radiation than was that of normal animals. Similar results were obtained by Valentine et al.2 using dogs and rats, and by Stohlman et al.3. Schack and MacDuffee4 showed that mice developed an increased resistance to radiation following a period of hypoxia sufficient to increase the erythroid elements in the bone marrow. Mathe and Bernard5 found that bleeding rats before irradiation, followed by post-irradiation transfusion of the same blood, seemed to offer some protection to the hæmopoietic system as judged by comparing their hæmatocrits and circulating reticulocyte numbers with those of control animals. Other experiments in this report indicated that injections of plasma of anæmic rats to irradiated litter mates within 1 hr. of exposure offered some protection to these animals on the 6th day after irradiation, Stohlman and Brecher6 using anaemic donor rats reported similar findings.
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References
Jacobson, L. O., Marks, E. K., Gaston, E. O., Simmons, E. L., and Block, M. H., Science, 107, 248 (1948).
Valentine, W. N., and Pearce, M. L., Blood, 7, 1 (1952). Valentine, W. N., Pearce, M. L., and Lawrence, J. S., ibid., 7, 14 (1952).
Stohlman, F., Cronkite, E. P., and Brecher, G., Proc. Soc. Exp. Biol. and Med., 88, 402 (1955).
Schack, J. A., and MacDuffee, R. C., Science, 110, 259 (1949).
Mathe, G., and Bernard, J., Rev. Hemat., 12, 507 (1957).
Stohlman, F., and Brecher, G., Proc. Soc. Exp. Biol. and Med., 91, 1 (1956).
Gordon, A. S., Physiol. Revs., 39, 1 (1959).
Gilding, H. P., Meyeratein, W., and Nutt, M. E., J. Physiol., 108, 32, P (1948).
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CUMMING, J., KHOYI, M. Effect of Plasma from Anæmic Rabbits on the Post-irradiation Anæmia of Mice. Nature 193, 1196–1198 (1962). https://doi.org/10.1038/1931196a0
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DOI: https://doi.org/10.1038/1931196a0
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