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Effect of Sheep Pituitary Extract on Hypercholesterolæmia in Intact and Hypophysectomized Rats

Abstract

THE prolonged administration of cortisone or adrenocorticotrophic hormone (ACTH) has sometimes been found to cause a change in the concentration of cholesterol in serum in human beings and in experimental animals. While some workers1,4 report that they have found such an elevation, others have noted no effect7; still others have reported the opposite3.

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BARAKAT, R. Effect of Sheep Pituitary Extract on Hypercholesterolæmia in Intact and Hypophysectomized Rats. Nature 192, 71–72 (1961). https://doi.org/10.1038/192071b0

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