Abstract
WHILE examining the hæmoglobin of hydrops and erythroblastosis fœtalis, in an attempt to correlate fœtal disease with hæmoglobin ‘Bart's’, five consecutive cases (four in Indonesia and one in Malaya) were found in which fœtal hydrops and erythroblastosis were associated with this type of hæmoglobin1,2. Four of these cases were examined in detail, and the sickling phenomenon was noted in the abnormal erythrocytes; the amounts of the abnormal fast-moving hæmoglobin were very high, and formed by far the major component. A small amount of hæmoglobin H was detected in all four specimens; no hæmoglobin S was detected in any of them. Hæmoglobin ‘Bart's’ is now believed to be identical with the Fessas and Papaspyrou type of hæmoglobin3–5.
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LUAN ENG, LI. Hæmoglobin ‘Bart's’ and the Sickling Phenomenon. Nature 191, 1314 (1961). https://doi.org/10.1038/1911314a0
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DOI: https://doi.org/10.1038/1911314a0
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