Abstract
THE changes in the liver during the acute stage of infective hepatitis consist of marked alterations to the liver cells, especially in the central regions of the lobule, and an infiltration of the portal tracts and sinusoids with inflammatory cells. Except in fatal cases, necrosis of liver cells is infrequent1–4. The disease is thought to be a virus infection of the hepatic parenchyma ; but the causative organism or organisms have so far eluded laboratory isolation5.
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BEARCROFT, W. The Liver in Infective Hepatitis. Nature 190, 549–550 (1961). https://doi.org/10.1038/190549a0
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DOI: https://doi.org/10.1038/190549a0
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