Abstract
THE importance of uronic acids in carbohydrate metabolism has only recently begun to be elucidated. The metabolism of inositol and ascorbate is known to involve uronic acid intermediates1,2, and nucleotide-bound glucuronic acid has been implicated in hyaluronic acid synthesis3.
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Charalampos, F. C., and Lyras, C., J. Biol. Chem., 228, 1 (1957).
Horowitz, H., and King, C., J. Biol. Chem., 205, 815 (1953).
Glaser, L., and Brown, D., Proc. U.S. Nat. Acad. Sci., 41, 5 (1955).
Strominger, J., Kalckar, H. M., Axelrod, J., and Maxwell, E. S., J. Amer. Chem. Soc., 76, 6411 (1954).
Marsh, C. A., J. Chem. Soc., 1578 (1952).
Dische, Z., J. Biol. Chem., 167, 189 (1947).
Dutton, G. J., and Storey, I. D. E., Biochem. J., 57, 275 (1954).
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JACOBSON, B., DAVIDSON, E. Chemical Oxidation of Uridine Diphosphate-Glucose to Uridine Diphosphate-Glucuronic Acid. Nature 189, 663 (1961). https://doi.org/10.1038/189663a0
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DOI: https://doi.org/10.1038/189663a0
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