Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Inactivation by Visible Light of Yeast sensitized by a Nucleic Acid Fluorochrome

Nature volume 186, pages 731–732 (1960)Cite this article

Abstract

PRECISE and reproducible survival curves have previously been obtained for haploid and diploid yeast irradiated with X-rays and with ultra-violet light1,2. Similar curves have now been obtained for the inactivation by visible light of yeast cells sensitized with the fluorescent diaminoacridine dye, acridine orange (3,6-bis-dimethylaminoacridine).

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Wood, T. H., Proc. Soc. Exp. Biol. Med., 84, 446 (1953).

    Article  CAS  Google Scholar 

  2. Uretz, R. B., Radiation Res., 2, 240 (1955).

    Article  ADS  CAS  Google Scholar 

  3. Latarjet, R., and Ephrussi, B., C.R. Acad. Sci., Paris, 229, 306 (1949).

    Google Scholar 

  4. Zirkle, R. E., and Tobias, C. A., Arch. Biochem. Biophys., 47, 282 (1953).

    Article  CAS  Google Scholar 

  5. Anderson, E. C., Armstrong, J. A., and Niven, J. S. F., Symp. Soc. Gen. Microbiol., 9, 224 (1959).

    Google Scholar 

  6. Albert, A., “The Acridines” (Arnold, London, 1951).

    Google Scholar 

  7. Jacoby, F., Medawar, P. B., and Willmer, E. N., Brit. Med. J., ii, 149 (1941).

  8. Lasnitzki, I., and Wilkinson, J. H., Brit. J. Cancer, 2, 369 (1948).

    Article  CAS  Google Scholar 

  9. Lettré, H., Angew. Chemie, 63, 421 (1951).

    Article  Google Scholar 

  10. De Bruyn, P. P. H., Robertson, R. C., and Farr, R. S., Anat. Rec., 108, 279 (1950).

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. DAVID FREIFELDER

    Present address: Department of Biology, Massachusetts Institute of Technology,

Authors and Affiliations

  1. Committee on Biophysics, University of Chicago, Chicago, 37

    DAVID FREIFELDER & ROBERT B. URETZ

Authors
  1. DAVID FREIFELDER
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. ROBERT B. URETZ
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

FREIFELDER, D., URETZ, R. Inactivation by Visible Light of Yeast sensitized by a Nucleic Acid Fluorochrome. Nature 186, 731–732 (1960). https://doi.org/10.1038/186731b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/186731b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing