Abstract
THE blood coagulation mechanism of the chicken appears to differ greatly from that of mammals, in that its clotting time can exceed 1 hr. Recent literature assumes the chicken to have a blood-clotting time in a range similar to the higher mammals. Dukes1 quotes Amendt (1922) as finding this to be 4.5 min. ; Johnson and Connor2 found an average of 6 min. 21 sec. with a range of 1–14 min. ; while Didisheim et al. 3 query their recorded time of 9 min. in glass and 10 min. with siliconized equipment at 37° C. Howell4, however, in 1909 infers that it is common knowledge that the blood of birds, terrapins and horses clots slowly. In 19405 he indicates that prolonged clotting time of hours or days in lower vertebrates (birds, reptiles and fishes) is due to the lack of “thromboplastic substance” within the vessels while prompt clotting is brought about by an active “thromboplastic tissue extract”.
Similar content being viewed by others
Article PDF
References
Dukes, H. H., “The Physiology of Domestic Animals”, 7, 55 (Cornell University Press, New York, 1955).
Johnson, E. P., and Connor, B. V., J. Amer. Vet. Med. Assoc., 83, New Ser., 37, 325 (1933).
Didisheim, P., Hatori, K., and Lewis, J. H., J. Lab. and Clin. Med., 53, 6, 866 (1959).
Howell, W. H., “A Textbook of Physiology”, 3 (W. B. Saunders Co., Philadelphia, 1909).
Howell, W. H., “A Textbook of Physiology”, 14 (1940).
Lee, R. I., and White, P. D., Amer. J. Med. Sci., 145, 495 (1913).
Quick, A. J., “The Hæmorrhagic Diseases” (Lea and Febiger, Philadelphia, 1957).
Biggs, R., and Macfarlane, R. G., “Human Blood Coagulation and its Disorders” (Charles Thomas, Springfield, Ill, 1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BIGLAND, C., TRIANTAPHYLLOPOULOS, D. A Re-Evaluation of the Clotting Time of Chicken Blood. Nature 186, 644 (1960). https://doi.org/10.1038/186644a0
Issue Date:
DOI: https://doi.org/10.1038/186644a0
This article is cited by
-
Ultrastructural alterations in thrombocytes of the snake Waglerophis merremii after Activation by ADP
Comparative Haematology International (1994)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.