Abstract
ALTHOUGH synthetic pathways of the L series of amino-acids have been studied extensively by the use of biochemical mutants of micro-organisms, there appears to be no published account of the synthesis of the D series of amino-acids using similar experimental techniques. Meanwhile, because D-glutamic acid is known to be an essential component of the cell wall and capsular fractions of a certain kind of bacteria1,2, an attempt to obtain mutants requiring D-glutamic acid for growth is still valuable. With this idea, induction and isolation of mutants from a wild strain of Bacillus subtilis K requiring D-glutamic acid was attempted.
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References
Work, E., Nature, 179, 841 (1957).
Thorne, C. B., “Bacterial Anatomy”, 68 (Cambridge University Press, 1956).
Gray, C. H., and Tatum, E. L., Proc. U.S. Nat. Acad. Sci., 30, 404 (1944).
Burkholder, P. R., and Giles, N. H., Amer. J. Bot., 34, 345 (1947).
Lederberg, J., and Lederberg, E. M., J. Bact., 63, 399 (1952).
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MOMOSE, H., IKEDA, Y. Isolation of Mutants of Bacillus subtilis requiring D-Glutamic Acid. Nature 186, 567–568 (1960). https://doi.org/10.1038/186567b0
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DOI: https://doi.org/10.1038/186567b0
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