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Fluorescent Schiff-Type Reagents for Cytochemical Detection of Polyaldehyde Moieties in Sections and Smears

Abstract

THE standard Schiff reagent (basic fuchsin plus sulphurous acid) has been used widely in cytochemistry to localize such aldehyde moieties as deoxyribonucleic acid by the Feulgen reaction and 1, 2 glycols (polysaccharides) by the periodic acid-Schiff reaction. Work in this laboratory designed to provide other reliable aldehyde-specific reagents (Schiff-type reagents) has been completed1,2.

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KASTEN, F., BURTON, V. & GLOVER, P. Fluorescent Schiff-Type Reagents for Cytochemical Detection of Polyaldehyde Moieties in Sections and Smears. Nature 184, 1797–1798 (1959). https://doi.org/10.1038/1841797a0

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