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Influence of the Thymus upon the Egg-White Allergy in the Rat

Abstract

IT has been shown previously that the thymus is extensively involved in the interaction between the anterior pituitary and the adrenal cortex1. Thus, the thymus was found a moderator of the corticotropic influence2, whereas it enhanced the influence of growth hormone3. The thymus was shown to be a synergist to deoxycorticosterone4. Furthermore, thymus atrophy following hypophysectomy was prevented with growth hormone injections5, and the changes of the thymus resulting from adrenalectomy was prevented by deoxycosterone (not by cortisone). These involvements of the thymus in the interaction between anterior pituitary and adrenal cortex made it probable that the thymus may exert an influence upon the course of inflammatory reaction.

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References

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COMSA, J. Influence of the Thymus upon the Egg-White Allergy in the Rat. Nature 184, 1726–1727 (1959). https://doi.org/10.1038/1841726a0

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