Abstract
EXCESS vitamin A ingestion increases bleeding tendency1, depresses basal metabolism2 and increases excretion of neutral 17-ketosteroids in urine of albino rats3. The Qo2 of liver slices of hypervitaminotic A rats is lower than that of control rats (Ray, Amal and Sadhu, D. P., unpublished observations), the weight of the thyroid is diminished and that of the adrenal increased2. In an attempt to elucidate the mechanism of hypometabolism induced in hypervitaminosis A, liver was studied for glycogen and fat contents and diaphragm as an index of glucose utilization in peripheral tissues.
Similar content being viewed by others
Article PDF
References
Poole, J. C. F., Quart. J. Exp. Physiol., 43, 427 (1958).
Sadhu, D. P., and Brody, S., Fed. Proc., 6, 420 (1947); Amer. J. Physiol., 149, 400 (1947).
Ray, Amal, and Sadhu, D. P., Ind. J. Physiol. and Allied Sci., 11, 1 (1957).
Sadhu, D. P., Nature, 177, 1236 (1956).
Garner, R. J., and Roberts, R., Biochem. J., 59, 224 (1955).
Sadhu, D. P., and Rruscott, B. Lionel, Endocrinol., 43, 120 (1948).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
RAY, A., SADHU, D. Carbohydrate Metabolism in Hypervitaminosis A.. Nature 184, 1323 (1959). https://doi.org/10.1038/1841323a0
Issue Date:
DOI: https://doi.org/10.1038/1841323a0
This article is cited by
-
Lipid Metabolism in Hypervitaminosis A
Nature (1966)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.