Abstract
THE unsatisfactory status of the important problem of the determination of ionized calcium in biological media has recently been re-appraised by W. F. and M. S. Neuman1. After critical examination of methods then existing and of available data on the medium most generally investigated, serum, they state that “the amount of ionized calcium in normal serum now seems to be pretty well established—approximately 1.3 mM/litre.”
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References
Neuman, W. F., and Neuman, M. W., “Chemical Dynamics of Bone Mineral” (University of Chicago Press, Chicago, Illinois, 1958).
Ettori, J., and Scoggan, S. M., Arch. Biochem. and Biophys., 78, 213 (1958).
Raaflaub, J., Hoppe-Seylers, Z. physiol. Chem., 288, 228 (1951).
McLean, F. C., and Hastings, A. B., J. Biol. Chem., 107, 337 (19..).
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ETTORI, J., SCOGGAN, S. Ionized Calcium in Biological Media. Nature 184, 1315–1316 (1959). https://doi.org/10.1038/1841315b0
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DOI: https://doi.org/10.1038/1841315b0
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