Abstract
IN 1941 Jacques and Waters mentioned the degranulation of mast cells in the liver of a dog undergoing anaphylactic shock1. In 1952 Stuart stated that the shock organs of anaphylaxis in the dog, rabbit, and guinea pig all contain mast cells which degranulate when a sensitized animal is injected with antigen2. Unfortunately, no details were given of the histological techniques he used. More recently, Mota and Vugman have reported some experiments from which it was concluded that anaphylaxis in the lung of the guinea pig caused a marked reduction in the number of mast cells histologically demonstrable in that organ3.
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References
Jacques and Waters, J. Physiol., 99, 454 (1941).
Stuart, Anat. Rec., 112, 394 (1952).
Mota and Vugman, Nature, 177, 427 (1956).
Gomori, “Microscopic Histochemistry” (University of Chicago Press, 1952).
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SMITH, W. Mast Cell Population of Lung of the Guinea Pig and other Tissues. Nature 184, 1154–1155 (1959). https://doi.org/10.1038/1841154a0
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DOI: https://doi.org/10.1038/1841154a0
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