Abstract
CERTAIN sulphydryl reagents such as ‘Salyrgan’1 and certain chelating agents such as ethylenediamine tetraacetate2,3 have been known to have a lengthening action on glycerinated muscle fibres in the presence of adenosine triphosphate. A reasonable explanation of this relaxing action by ‘Salyrgan’ has already been given1. The chelating actions of ethylenediamine tetraacetate and its analogues are of interest. We have reported4, however, using seven different chelating agents, that their chelating activities were not parallel with their relaxing capacities. Thus the mechanism of these agents remains unsolved.
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EBASHI, S., EBASHI, F. Relaxation of Glycerol-treated Muscle Fibres by Acetone. Nature 183, 687–688 (1959). https://doi.org/10.1038/183687b0
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DOI: https://doi.org/10.1038/183687b0
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