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Oral Induction of Leukæmia in Mice

Abstract

THE induction of leukæmia by parenteral inoculation of cell-free brain filtrates has been demonstrated1,2. Speculation as to the natural route of transmission of leukæmia led to the exploration of the leukæmogenic effect of whole brains and cell-free brain filtrates when given orally.

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References

  1. Schoolman, H. M., Spurrier, W., Schwartz, S. O., and Szanto, P. B., Blood, 12, 694 (1957).

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  2. Schwartz, S. O., Schoolman, H. M., and Spurrier, W., J. Lab. and Clin. Med., 53, 233 (1959).

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  3. Schwartz, S. O., Schoolman, H. M., Spurrier, W., and Yates, L., Proc. Soc. Exp. Biol. and Med., 97, 397 (1958).

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MADUROS, B., SPURRIER, W. & SCHWARTZ, S. Oral Induction of Leukæmia in Mice. Nature 183, 1816–1817 (1959). https://doi.org/10.1038/1831816a0

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  • DOI: https://doi.org/10.1038/1831816a0

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