Abstract
IN previous investigations on the anterior pituitary of rats intoxicated with benzene we found histochemical changes suggesting an increased hormone secretion from both the acidophil cells and the beta cells1. Since the beta cells are believed to be concerned in the rat with the secretion of thyrotrophic hormone and are therefore also called thyrotrophs2,3, it seemed of interest to determine whether the hyperfunction of the pituitary beta cells is paralleled by cytological signs of augmented activity in their target gland, the thyroid.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Iannaccone, A., and Cicchella, G., J. Endocrinol. (in the press).
Purves, H. D., and Griesbach, W. E., Endocrinol., 49, 244 (1951).
Halmi, N. S., Endocrinol., 50, 140 (1952).
Allara, E., “Aspetti istologici dei processi secretori nelle ghiandole endocrine” (Macrì, Florence, 1954).
Gross, J., “International Review of Cytology”, edit. by Bourne, G. H., and Danielli, J. F., 6, 265 (Academic Press, New York, 1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
IANNACCONE, A., CICCHELLA, G. Effect of Benzene on Rat Thyroid. Nature 182, 669–670 (1958). https://doi.org/10.1038/182669a0
Issue Date:
DOI: https://doi.org/10.1038/182669a0
This article is cited by
-
Wirkung der chronischen benzolvergiftung auf das zentralnervensystem bei verschiedener di�t
Internationales Archiv f�r Gewerbepathologie und Gewerbehygiene (1964)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
