Abstract
USING starch-gel electrophoresis, Smithies has discovered several β-globulin patterns in human plasma. He refers to these as βC, βBC, βCD and βD 1,2. βC is the type most commonly found, but βBC occurred in about 1 per cent of Canadians and βCD in about 4 per cent of American Negroes and even more frequently in Australian Aboriginals. The formation of the different β-globulins B, C and D appears to be genetically controlled and Smithies suggests that each may be determined by one of three allelic genes.
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References
Smithies, O., Nature, 180, 1482 (1957).
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Poulik, M., Nature, 180, 1477 (1957).
Poulik, M., and Smithies, O., Biochem. J., 68, 636 (1958).
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HARRIS, H., ROBSON, E. & SINISCALCO, M. β-Globulin Variants in Man. Nature 182, 452 (1958). https://doi.org/10.1038/182452a0
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DOI: https://doi.org/10.1038/182452a0
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