Abstract
CLINICALLY, the view is widely held that major surgical operations may encourage the growth of metastases in patients with certain types of cancer (stage III breast carcinoma, Wilm's tumour, bone and soft tissue sarcomas). It is possible that operative stress may favour the spread of tumours by affecting the adhesion between cells. In view of the known relation between lack of adhesiveness and low calcium content1, an investigation of calcium and phosphorus metabolism in patients undergoing surgery has been undertaken.
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References
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Bronner, F., Harris, R. S., Maletskos, C. J., and Benda, C. E., J. Clin. Invest., 35, 78 (1956).
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STARR, K., WYNNE, K. & CHORLTON, S. Calcium and Phosphorus Metabolism after Surgery. Nature 182, 1505–1506 (1958). https://doi.org/10.1038/1821505a0
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DOI: https://doi.org/10.1038/1821505a0
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