Abstract
RECENT observations have indicated that reserpine can depress not only 5-hydroxytryptamine, but also noradrenaline- and adrenaline-levels in brain, heart, spleen and other sympathetically innervated tissues1–3. The depletion of adrenal medullary hormones by single doses of reserpine has been attributed to a stimulation of centres in the central nervous system, since spinal transection at T 1 is reported to prevent this response1.
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MIRKIN, B. Catechol Amine Depletion in the Rat's Denervated Adrenal Gland following Chronic Administration of Reserpine. Nature 182, 113–114 (1958). https://doi.org/10.1038/182113a0
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DOI: https://doi.org/10.1038/182113a0
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