Abstract
THE corneo-fundal potential (that is, the steady potential difference across the eye) was discovered in 1849 by Du Bois-Reymond1. Noell2 has recently shown evidence that a part of the corneo-fundal potential is attributable to the membrane polarization of the pigment epithelium adjacent to the sensory cells of the retina. He found, while measuring the retinogram in rabbits, polarization changes lasting for more than 200 sec. following the onset of illumination. An analogous phenomenon, described in detail below, occurs in humans.
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References
Du Bois-Reymond, E., “Untersuchungen über thierische Elektrizität”, 2, Pt. 1, 256 (G. Reimer, Berlin, 1849).
Noell, W. K., U.S.A.F. School of Aviation Medicine, Project No. 21-1201-0004, Report No. 1 (October 1953).
Mowrer, O. H., Ruch, T. C., and Miller, N. E., Amer. J. Physiol., 114, 423 (1936).
Miles, W. R., Proc. U.S. Nat. Acad. Sci., 25, 128 (1939).
Kris, C., Aero-Medical Laboratory, Wright Air Development Command, Contract AF 33(616)-3849, Final Technical Report (July 1957).
Kris, C., Soc. Proc., Eastern Assoc., J. EEG Clin. Neurophysiol., 9, 382 (1957).
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KRIS, C. Corneo-Fundal Potential Variations during Light and Dark Adaptation. Nature 182, 1027–1028 (1958). https://doi.org/10.1038/1821027a0
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DOI: https://doi.org/10.1038/1821027a0
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