Abstract
BECAUSE of the importance of cardiac output and its relation to an individual's physical condition, it would be valuable to have a reliable relationship between the cardiac output of an animal or human being and his central pressure cycle at any moment and condition of interest. The only available formula of that type that is essentially scientific is one for stroke volume, due to Frank1, namely, in which V s is the stroke volume (cm.3), A is the central patent cross-section (cm.2), t s is the duration of systole (sec.), Δp is the pulse pressure (dynes/cm.2), and c is the propagation velocity of the pulse wave (cm./sec.).
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References
Frank, Otto, Z. Biol., 90, 405 (1930).
Frank, Otto, Z. Biol., 86, 91 (1926).
Warner, H. R., Swan, H. J. C., Connolly, D. C., Tompkins, R. G., and Wood, E. H., J. App. Physiol., 5, 495 (1953).
Kroeker, E. J., and Wood, E. H., Circ. Res., 3, 623 (1955).
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EVANS, R. Cardiac Output and Central Pressure Data. Nature 181, 1471–1472 (1958). https://doi.org/10.1038/1811471a0
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DOI: https://doi.org/10.1038/1811471a0
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